To run OpenSim with more than one region in a OpenSim instance on macOS you might need to increase the max allowed files open and/or processes per logged in user.
Placing the two files in the zip file inside
Placing the two files in the zip file inside
/Library/LaunchDaemons
will set the maximum allowed open files to 65536 and maximum allowed processes per logged in user to 2048 at the system level on system startup.